Boston Red Sox vs. New York Yankees MLB prediction, odds, best bets for Friday Night

The New York Yankees will face off against the dreaded Boston Red Sox at Yankee Stadium on Friday, scheduled to start at 7:05 p.m. ET. Will Warren gets the start for the Yankees, while the Red Sox will trot out Walker Buehler. Our best bet? Under 9 runs (-102).

This preview includes Dimers’ best bets and predicted scoreline for the New York Yankees vs. Boston Red Sox, based on 10,000 simulations runs early Friday morning.

Local Yankees fans can use the BetMGM bonus code “SILIVE150″ to unlock betting bonuses for tonight’s game, while fans elsewhere can use the BetMGM bonus code “CUSE150,″ or Bet365 bonus code “SYRACUSE,” as reported by our colleagues at Syracuse.com.

Red Sox vs. Yankees betting preview

Utilize the interactive widget below to discover the current run line, total, and moneyline betting odds and probabilities for the Red Sox-Yankees game at Yankee Stadium.

This prediction and best bet for Friday’s MLB matchup between the Red Sox and Yankees is from Dimers.com, a leader in sports betting predictions.

Check out all the important details on today’s game, including each team’s starting pitcher, as well as the best odds sourced from the top sportsbooks in the country.

Game details

The key information you need before the Red Sox vs. Yankees MLB game.

Teams: Boston Red Sox vs. New York Yankees
Date: Friday, June 6, 2025
Time: 7:05 p.m. ET
Location: Yankee Stadium

Starting pitchers

Red Sox: Walker Buehler (4-3, 4.44 ERA)
Yankees: Will Warren (3-3, 5.19 ERA)

Odds

The latest and best odds for the MLB matchup between the Red Sox and Yankees.

Run line: Red Sox +1.5 (-134), Yankees -1.5 (+125)
Moneyline: Red Sox +150, Yankees -170
Total: Over/Under 9 (-112/-102)

The odds and lines presented in this article are the best available from selected sports betting sites at the time of publication and are subject to change.

Expert prediction: Red Sox vs. Yankees

Using trusted data analysis and advanced algorithms, the experts at Dimers have executed 10,000 simulations of Friday’s Red Sox vs. Yankees game.

According to Dimers’ popular predictive analytics model, the Yankees are more likely to defeat the Red Sox at Yankee Stadium. This prediction is based on the model giving the Yankees a 61% chance of winning the game.

Furthermore, Dimers predicts that the Red Sox (+1.5) have a 59% chance of covering the run line, while the 9-run over/under has a 52% chance of staying under.

As always, these predictions and probabilities are correct at the time of publication but are subject to potential changes.

Red Sox vs. Yankees best bet

Our top pick for the Red Sox vs. Yankees game on Friday is to bet on Under 9 runs (-102).

This expert betting advice is formulated through detailed modeling and valuable betting intelligence, designed to deliver you the best possible plays.

MLB Friday: Red Sox vs. Yankees

Get ready for Friday’s action between the Red Sox and Yankees inMLB at Yankee Stadium, which is scheduled to start at 7:05 p.m. ET. MLB picks and MLB props are popular aspects of the oldest of America’s major professional sports organizations, Major League Baseball. The Red Sox and Yankees are among MLB’s esteemed 30 teams, with 29 based in the United States and one in Canada.

We emphasize that all of the MLB best bets and MLB predictions in this article are derived from 10,000 data-driven simulations of the Red Sox vs. Yankees matchup, and they are accurate at the time of publication. They aim to help you make more informed choices when placing bets at online sportsbooks.

Please note that when engaging in online betting, it is important to exercise responsible gambling practices and seek reputable sources for accurate and up-to-date information.